IKO Articles
Find clear answers to common questions about kava, including safety facts, regulatory status, and history. Trusted information from the International Kava Organization (IKO)
Comprehensive Guide to Protecting ‘Awa (Kava) Plants from Cucumber Mosaic Virus (CMV)
Cucumber mosaic virus (CMV) is a pervasive threat to the cultivation of ‘awa (kava, Piper methysticum), with devastating effects on plant health and productivity. This viral pathogen, transmitted through insect vectors and infected plant material, can severely compromise the quality and yield of ‘awa, a
The Michael Reaction, Glutathione, and Kava Hepatotoxicity: An Analysis
Introduction Kava is renowned for its calming effects and has been used for centuries in the South Pacific. Its pharmacological effects are primarily attributed to a group of compounds known as kavalactones. From 1998 to 2003 concerns emerged regarding the potential hepatotoxicity (liver toxicity) of
Persistence is Key: Traditional Kava Powder + Water + Strained = Food
Kava as a food, and who we have to thank. After the previous announcement of how the FDA has accepted and ratified the codex definition of kava when mixed with water and strained, we should take a closer look at the Codex document itself, and
Evolution of FDA Regulations on Kava: Acknowledging Tradition and Ensuring Safety
FDA now accepts the Codex Definition of Kava Consumption. The classification and regulatory stance of the U.S. Food and Drug Administration (FDA) on Kava has evolved significantly over the years. Kava, scientifically known as Piper methysticum, has been traditionally used by Pacific Islanders for its

A Kava Lounge Podcast – Part 1 – Nancy J Pollock Discussion.
The Kava Lounge Podcast “The Kava Lounge,” hosted by Kavasseur and Jimmy Price, is a unique podcast dedicated to exploring the diverse world of Piper methysticum, commonly known as kava. The show’s format is both engaging and educational, aiming to fill the gap in entertaining
Director Introductions
In this video, you’ll gain a deeper understanding of the personal motivations, experiences, and visions that drive these directors. Their stories are not just about kava; they’re about overcoming challenges, building communities, and forging a sustainable and respectful future for the kava industry. Join us as we explore their contributions and the exciting future they envision for kava enthusiasts around the world.

One of the Best Looks Into Kavalactone Interactions at the GABA-A Receptor from 1998.
A review of a study that delves into the pharmacological activities of kava, focusing on kavalactones and their interaction with the GABAA receptor. The study concludes that kavapyrones do not directly interact with benzodiazepine or GABAA receptors.

Behind the Scenes: Understanding Cytochrome P450’s Vital Function in Drug Metabolism
Cytochrome P450 enzymes play a pivotal role in drug metabolism, affecting not just the efficacy but also the safety of drugs. Their activity can be influenced by various factors, including age and disease states, and they are a key player in drug-drug interactions.

2021 Study of Kava Extract Into the MAO-B Inhibitory Properties.
The study investigates the inhibitory effects of Kava extract on monoamine oxidase B activity in mice, suggesting its potential therapeutic applications.
